https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52849 Wed 14 Feb 2024 15:39:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39963 Thu 30 Jun 2022 16:35:31 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44455 Thu 13 Oct 2022 15:15:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38568 2O4, CoFe₂O₄ and Fe_3,O₄) coated with PEG for MNF formulation and evaluated the loading/release efficacy of doxorubicin (DOX), an anticancer drug. We have presented in detail the drug loading capacity and the time-dependent cumulative drug release of DOX from PEG-coated MNPs based MNFs. Specifically, we have selected three different MNPs (NiFe₂O₄, CoFe₂O₄ and Fe₃O₄) coated with PEG for the MNFs and compared their variance in the loading/release efficacy of DOX, through experimental results fitting into mathematical models. DOX loading takes the order in the MNFs as CoFe₂O₄ > NiFe₂O₄ > Fe₃O₄. Various drug release models were suggested and evaluated for the individual MNP based NFs. While the non-Fickian diffusion (anomalous) model fits for DOX release from PEG coated CoFe₂O₄, PEG coated NiFe₂O₄ NF follows zero-order kinetics with a slow drug release rate of 1.33% of DOX per minute. On the other hand, PEG coated NiFe₂O₄ follows zero-order DOX release. Besides, several thermophysical properties and magnetic susceptibility of the MNFs of different concentrations have been studied by dispersing the MNPs (NiFe₂O₄, CoFe₂O₄ and Fe₃O₄) in the base fluid at 300 K under ultrasonication. This report on the DOX loading/release capability of MNF will set a new paradigm in view that MNF can resolve problems related to the self-heating of drug carriers during mild laser treatment with its thermal conducting properties.]]> Thu 04 Nov 2021 13:58:14 AEDT ]]>